Singapore will be the fastest ageing country by 2025, with 25% of its population estimated to be above 65 years old by 2030. Although medical advancements have managed to improve life expectancy among Singaporeans, our quality of life, or healthspan, doesn’t speak so. The grim reality is that Singaporeans are spending about 10 years of their twilight years in poor health. As such, one should improve the quality of life by delaying ageing combined with lifestyle intervention. This will allow for better early detection, development of personalised, preventive and therapeutic strategies to improve healthspan. Through such an approach, not only the quality of life and life expectancy increases, healthcare and caregiving costs will be more sustainable in the long run.